Characteristics of repeat syphilis infections and interinfection intervals in a retrospective clinical cohort: implications for syphilis retesting and prevention

Among MSM, syphilis reinfections were common, especially among PLWH and HIV-negative PrEP users, with the latter having the shortest interval between infections. These groups should be retested for syphilis with frequent serological screening, <i>Treponema pallidum</i> PCR testing of syphilis lesions and should be targeted for syphilis prevention.

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Publication Details

Journal
Sexually Transmitted Infections
Published
2025-08-12
DOI
https://doi.org/10.1136/sextrans-2025-056577
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Characteristics of repeat syphilis infections and interinfection intervals in a retrospective clinical cohort: implications for syphilis retesting and prevention

Eric P. F. Chow, Christopher Kincaid Fairley, Janet M Towns, Stephen Graves et al.
Sexually Transmitted Infections
Syphilis Diagnosis and Treatment
article

Characteristics of repeat syphilis infections and interinfection intervals in a retrospective clinical cohort: implications for syphilis retesting and prevention

Eric P. F. Chow, Christopher Kincaid Fairley, Janet M Towns, Stephen Graves, Tzu-Yen Evelyn Huang, Marcus Y. Chen, Francesca Azzato
article en

Abstract

Among MSM, syphilis reinfections were common, especially among PLWH and HIV-negative PrEP users, with the latter having the shortest interval between infections. These groups should be retested for syphilis with frequent serological screening, <i>Treponema pallidum</i> PCR testing of syphilis lesions and should be targeted for syphilis prevention.

Sexually Transmitted Infections
Barwon Health (AU), Melbourne Sexual Health Centre (AU), Peter Doherty Institute (AU), Monash University (AU)
National Health and Medical Research Council
Openalex Percentile: Top 74%
Syphilis Diagnosis and Treatment
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