Evaluation of the Effect of Tranexamic Acid on Meniscus Healing and Articular Cartilage in a Rabbit Model
This rabbit study found that TXA administration did not enhance healing following meniscus repair. Moreover, intra-articular TXA appeared to have exerted an adverse effect on articular cartilage, possibly due to the detrimental effects of persistent blood in a joint. Further studies will be critically important to determine the effect of TXA administration at various time points after surgical repair.
Authors
- Ian D. Hutchinson (ORCID: https://orcid.org/0000-0002-3410-9288)
- M. Sama (ORCID: https://orcid.org/0009-0006-0956-8155)
- Ryan Healy (ORCID: https://orcid.org/0000-0001-8029-5221)
- Janice Havasy (ORCID: https://orcid.org/0000-0002-5013-3085)
- Vincent Yao (ORCID: https://orcid.org/0000-0002-1883-6434)
- Yulei Liu (ORCID: https://orcid.org/0000-0002-8177-1573)
- Scott Alan Rodeo (ORCID: https://orcid.org/0000-0002-0745-9880)
- Xiang‐Hua Deng (ORCID: https://orcid.org/0000-0003-3218-3182)
- Alexander N. Piacentini (ORCID: https://orcid.org/0000-0002-9048-3549)
- Jonathan Sgaglione (ORCID: https://orcid.org/0000-0001-7391-2383)
- Ronak M. Patel (ORCID: https://orcid.org/0000-0003-4676-5634)
Institutions
- Hospital for Special Surgery (US)
- Hofstra University (US)
Publication Details
- Journal
- HSS Journal® The Musculoskeletal Journal of Hospital for Special Surgery
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1177/15563316251357603
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00