Prevalence and prognostic implications of the Valve Academic Research Consortium-High Bleeding Risk criteria in patients undergoing transcatheter aortic valve implantation
Up to 60% of patients undergoing TAVI are at high or very high bleeding risk. The VARC-HBR criteria identified those at greater risk of adverse events. In-hospital bleeding complications and long-term cardiovascular events increased progressively across VARC-HBR categories.
Authors
- Francesco Bendandi
- Davide Cao (ORCID: https://orcid.org/0000-0001-7755-4069)
- Marco Barbanti (ORCID: https://orcid.org/0000-0002-4903-5437)
- Samantha Sartori (ORCID: https://orcid.org/0000-0003-0618-9409)
- Roxana Mehran (ORCID: https://orcid.org/0000-0002-5546-262X)
- Arnaldo Dimagli (ORCID: https://orcid.org/0000-0003-0055-8656)
- Umberto Benedetto (ORCID: https://orcid.org/0000-0002-7074-7949)
- Marco Sandri (ORCID: https://orcid.org/0000-0002-1422-5695)
- Wojciech Wojakowski (ORCID: https://orcid.org/0000-0002-3681-5207)
- Andrea Macchione
- Timo Mäkikallio (ORCID: https://orcid.org/0000-0002-6593-116X)
- Fabrizio D’Ascenzo (ORCID: https://orcid.org/0000-0002-6646-9317)
- Francesco Pelliccia (ORCID: https://orcid.org/0000-0003-1260-1308)
- Mario García‐Gómez (ORCID: https://orcid.org/0000-0001-6873-4869)
- Ciro Indorfi
- Ignacio Jesus Amat-Santos (ORCID: https://orcid.org/0000-0002-2311-4129)
- Fabio Miraldi (ORCID: https://orcid.org/0000-0002-2404-3369)
- Vincenzo Pasceri (ORCID: https://orcid.org/0000-0001-7409-5792)
- Fausto Biancari (ORCID: https://orcid.org/0000-0001-5028-8186)
- Luca Testa (ORCID: https://orcid.org/0000-0003-4687-3686)
- George Dangas (ORCID: https://orcid.org/0000-0001-7502-8049)
- Corrado Tamburino (ORCID: https://orcid.org/0000-0002-4940-9742)
- Marco Zimarino (ORCID: https://orcid.org/0000-0001-5455-6010)
- Giuliano Costa (ORCID: https://orcid.org/0000-0003-3770-8988)
- Francesco Bedogni (ORCID: https://orcid.org/0000-0002-4975-6605)
- Philippe Garot (ORCID: https://orcid.org/0009-0001-8960-7006)
- Carmen Spaccarotella (ORCID: https://orcid.org/0000-0003-1825-0510)
- Tatu Juvonen
- Federico Conrotto (ORCID: https://orcid.org/0000-0002-5402-6826)
- Giulio Stefanini (ORCID: https://orcid.org/0000-0002-3558-6967)
- Vincenzo De Marzo (ORCID: https://orcid.org/0000-0002-8031-9761)
- Italo Porto (ORCID: https://orcid.org/0000-0002-9854-5046)
- Wojciech Wańha (ORCID: https://orcid.org/0000-0003-1220-9496)
- Francesco Radico (ORCID: https://orcid.org/0000-0001-9177-9547)
- Giampaolo Luzi (ORCID: https://orcid.org/0009-0005-3881-168X)
- Eugenio Stabile (ORCID: https://orcid.org/0000-0001-9125-8813)
- Francesco Saia (ORCID: https://orcid.org/0000-0001-9969-2649)
- Davide Capodanno (ORCID: https://orcid.org/0000-0002-5156-7723)
- Marie‐Claude Morice
- Franco Fabbiocchi (ORCID: https://orcid.org/0009-0008-7656-6795)
- Michele La Torre
- David Hildick‐Smith
Institutions
- University of Helsinki (FI)
- Humanitas University (IT)
- Medical University of Silesia (PL)
- Cornell University (US)
- Università degli Studi di Enna Kore (IT)
- Royal Sussex County Hospital (GB)
- Helsinki University Hospital (FI)
- Magna Graecia University (IT)
- University of Chieti-Pescara (IT)
- Cardiovascular European Research Center (FR)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Centro Cardiologico Monzino (IT)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
- Ospedale San Filippo Neri (IT)
- IRCCS Policlinico San Donato (IT)
- Mount Sinai Hospital (US)
- Istituto Clinico Sant'Ambrogio (IT)
- South Karelia Central Hospital (FI)
- Federico II University Hospital (IT)
- Azienda USL di Bologna (IT)
- Policlinico Universitario di Catania (IT)
- Nippon Sheet Glass (Italy) (IT)
- Institut Cardiovasculaire Paris Sud (FR)
- Ospedale Policlinico San Martino (IT)
- Hôpital Privé Jacques Cartier (FR)
- Hospital Clínico Universitario de Valladolid (ES)
- Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" (IT)
- IRCCS Humanitas Research Hospital (IT)
- Azienda Ospedaliera Carlo Poma (IT)
- Agenzia Sanitaria Regionale Abruzzo (IT)
- Weill Cornell Medicine (US)
- University of Brescia (IT)
- University of Genoa (IT)
- Sapienza University of Rome (IT)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Heart
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1136/heartjnl-2025-326043
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00