The burden of cognitive impairment
The lifetime burden of cognitive impairment (CI) was estimated at $124,000 per capita, totaling $627 billion in aggregate-with 59% attributed to Alzheimer's disease and related dementias (ADRD) and 41% to mild cognitive impairment (MCI). Early-onset CI (before age 65) carried the highest per capita burden at $376,000, with these individuals living with MCI for about 13 years-over 7 years longer than those with late-onset CI. Significant disparities exist in CI burden, with racial/ethnic minorities and those without a high school degree experiencing disproportionately higher burden. Despite representing just 36% of the CI population, non-White individuals accounted for 47% of the aggregate CI burden.
Authors
- Hanke Heun‐Johnson (ORCID: https://orcid.org/0000-0002-4101-2492)
- Ritika Chaturvedi (ORCID: https://orcid.org/0000-0002-0416-6134)
- Darius Lakdawalla (ORCID: https://orcid.org/0000-0001-5934-8042)
- Dana P. Goldman (ORCID: https://orcid.org/0000-0001-8498-6396)
- Tadeja Gračner (ORCID: https://orcid.org/0009-0003-1285-4468)
- PhuongGiang Nguyen (ORCID: https://orcid.org/0000-0003-1638-1584)
- Bryan Tysinger (ORCID: https://orcid.org/0000-0002-8497-3664)
Institutions
- University of Southern California (US)
- RAND Corporation (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/alz.70436
- Citations
- 4
- Primary Topic
- Health and Well-being Studies
- Type
- article
- Field-Weighted Citation Impact
- 9.23
Funders
- U.S. National Library of Medicine