Estimated Small, Dense LDL Cholesterol and Atherosclerotic Cardiovascular Risk in the UK Biobank
In a UK Biobank cohort for primary prevention, the risk of all-cause ASCVD was better captured by E-sdLDL-C than LDL-C. It was also more predictive than LDL-C and ApoB when discordant with these 2 measures. E-sdLDL-C, which can be freely and automatically calculated from a standard lipid panel, can potentially improve ASCVD risk assessment without additional laboratory testing.
Authors
- Anna T Wolska (ORCID: https://orcid.org/0000-0001-9479-0741)
- Maureen Sampson
- Rafael Zubirán
- Alan T. Remaley (ORCID: https://orcid.org/0000-0003-2473-5549)
Institutions
- National Heart, Lung, and Blood Institute (US)
- National Institutes of Health Clinical Center (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1161/atvbaha.125.323157
- Citations
- 11
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 22.07