Association between homocysteine levels and hypertension prevalence as well as all-cause mortality and cardiovascular mortality among hypertensive patients: A population-based study

Our research validates Hcy as an independent risk factor for hypertension, further confirming a nonlinear positive correlation between blood pressure and Hcy levels. HHcy was associated with small increases SBP and DBP proportional to the degree of homocysteine elevation. Additionally, HHcy was a high-risk factor for all-cause and cardiovascular mortality in hypertensive patients. This may provide new insights into the management and treatment of hypertension.

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Journal
PLoS ONE
Published
2025-08-12
DOI
https://doi.org/10.1371/journal.pone.0330267
Primary Topic
Folate and B Vitamins Research
Type
article
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0.00
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article

Association between homocysteine levels and hypertension prevalence as well as all-cause mortality and cardiovascular mortality among hypertensive patients: A population-based study

Huan Yin, Wenna Wang, Peng Pu, Hao Lü et al.
PLoS ONE
Folate and B Vitamins Research
article

Association between homocysteine levels and hypertension prevalence as well as all-cause mortality and cardiovascular mortality among hypertensive patients: A population-based study

Huan Yin, Wenna Wang, Peng Pu, Hao Lü, Linlin Huang
article en

Abstract

Our research validates Hcy as an independent risk factor for hypertension, further confirming a nonlinear positive correlation between blood pressure and Hcy levels. HHcy was associated with small increases SBP and DBP proportional to the degree of homocysteine elevation. Additionally, HHcy was a high-risk factor for all-cause and cardiovascular mortality in hypertensive patients. This may provide new insights into the management and treatment of hypertension.

PLoS ONEVol. 20(8)
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), First People's Hospital of Chongqing (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 68%
Folate and B Vitamins Research
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