Association between homocysteine levels and hypertension prevalence as well as all-cause mortality and cardiovascular mortality among hypertensive patients: A population-based study
Our research validates Hcy as an independent risk factor for hypertension, further confirming a nonlinear positive correlation between blood pressure and Hcy levels. HHcy was associated with small increases SBP and DBP proportional to the degree of homocysteine elevation. Additionally, HHcy was a high-risk factor for all-cause and cardiovascular mortality in hypertensive patients. This may provide new insights into the management and treatment of hypertension.
Authors
- Huan Yin (ORCID: https://orcid.org/0000-0001-8755-3350)
- Wenna Wang
- Peng Pu (ORCID: https://orcid.org/0000-0003-0502-0513)
- Hao Lü (ORCID: https://orcid.org/0009-0007-6094-458X)
- Linlin Huang
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1371/journal.pone.0330267
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00