Early-life and adult body mass index in relation to MS disability progression
High BMI at diagnosis was associated with faster disability progression, particularly when present since early adulthood. These findings underscore the potential benefits of early weight management in MS.
Authors
- Tomas Olsson (ORCID: https://orcid.org/0000-0002-2938-1877)
- Eva Johansson (ORCID: https://orcid.org/0000-0001-6695-7989)
- Lars S. Alfredsson (ORCID: https://orcid.org/0000-0003-1688-6697)
- Anna Karin Hedström (ORCID: https://orcid.org/0000-0002-6612-4749)
- Jie Guo (ORCID: https://orcid.org/0000-0001-6104-9957)
Institutions
- Karolinska Institutet (SE)
- Centre for Palaeogenetics (SE)
- China Agricultural University (CN)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1007/s00415-025-13319-2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Margareta af Ugglas Foundation
- Swedish Foundation for MS Research
- Hjärnfonden
- Karolinska Institutet
- Vetenskapsrådet
- Medicinska Forskningsrådet
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd