Efficacy and Safety of Radiotherapy and Systemic Treatments in Adrenocortical Carcinoma: Systematic Review and Meta-Analysis
Mitotane significantly improves survival outcomes in patients with ACC, while radiotherapy exhibits potential benefits, particularly in localized disease. Further research is needed to verify the efficacy of cytotoxic chemotherapy, and randomized controlled trials are required to provide robust evidence of different treatment approaches.
Authors
- Tamás Kói (ORCID: https://orcid.org/0000-0003-0775-1088)
- Miklós Garami (ORCID: https://orcid.org/0000-0003-4298-2746)
- Andrea Párniczky (ORCID: https://orcid.org/0000-0003-3466-4780)
- Péter Hegyi (ORCID: https://orcid.org/0000-0003-0399-7259)
- Márk Hernádfői (ORCID: https://orcid.org/0009-0007-8653-2292)
- András Fogarasi (ORCID: https://orcid.org/0000-0001-8397-8706)
- D. I. Bako
- A. Pfeffer
- Nóra Beke
Institutions
- Semmelweis University (HU)
- Budapest University of Technology and Economics (HU)
- Heim Pál Országos Gyermekgyógyászati Intézet (HU)
- Bethesda Gyermekkórház (HU)
- Országos Korányi Tbc és Pulmonológiai Intézet (HU)
- University of Pecs (HU)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-08-10
- DOI
- https://doi.org/10.1210/clinem/dgaf457
- Citations
- 1
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 2.01