Pharmacokinetic Interactions Between Ethanol and PT150, a Selective Glucocorticoid Receptor Antagonist, in Healthy Volunteers
These data suggest that coadministration of PT150 and alcohol does not produce significant pharmacokinetic interactions, supporting the feasibility of evaluating PT150 in future clinical trials for alcohol use disorder.
Authors
- Christopher D. Verrico (ORCID: https://orcid.org/0000-0002-8272-0778)
- Cassius K. Mensah
- Tracy L. Nolen (ORCID: https://orcid.org/0000-0003-2512-343X)
- Jon F. Pennycuff
- Rick L. Williams (ORCID: https://orcid.org/0000-0002-1376-3416)
- Thomas R. Kosten (ORCID: https://orcid.org/0000-0003-1505-555X)
- Adetola O Vaughan (ORCID: https://orcid.org/0000-0002-5322-9744)
- Dewleen G. Baker (ORCID: https://orcid.org/0000-0002-1736-9838)
- Kayla J. Nowak (ORCID: https://orcid.org/0000-0002-2640-9432)
- Sandy S. Venneman
- Victoria Risborough
Institutions
- Michael E. DeBakey VA Medical Center (US)
- RTI International (US)
- University of California San Diego (US)
- Health Services Research & Development (US)
- VA San Diego Healthcare System (US)
- Systématique, adaptation, évolution (FR)
Publication Details
- Journal
- Journal of Addiction Medicine
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1097/adm.0000000000001557
- Citations
- 1
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 1.11