Ultrasonographic Features of Amyloid Arthropathy in Light ChainAmyloidosis: A Case Report
This case underscored key ultrasonographic features of amyloid arthropathy, including synovial thickening with heterogeneous echogenic deposits, tenosynovitis, and subacromialsubdeltoid bursa involvement. Unlike rheumatoid arthritis, amyloidosis lacked erosions and power Doppler signal, highlighting imaging distinctions. The hypoechoic inguinal amyloidoma with calcifications further aligned with amyloid deposition. Although amyloidosis shares certain clinical features with dialysis-related β2-microglobulin amyloidosis (e.g., carpal tunnel syndrome, shoulder deposits), AL amyloidosis may exhibit unique patterns, such as diffuse synovial infiltration without hyperemia. However, ultrasound's non-specificity necessitates histopathological confirmation. While systemic amyloidosis requires pathological confirmation, ultrasonography provides a rapid, cost-effective tool for early diagnostic guidance.
Authors
- Malek Dhifallah (ORCID: https://orcid.org/0000-0002-8023-7096)
- I. Gharsallah
Institutions
- Military Hospital of Tunis (TN)
- Tunis El Manar University (TN)
Publication Details
- Journal
- Current Rheumatology Reviews
- Published
- 2025-06-27
- DOI
- https://doi.org/10.2174/0115733971366804250619214510
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00