Efficacy of Low-Intensity Transcranial Ultrasound Stimulation in Enhancing Motor Recovery via Modulation of Microglial Polarization, Angiogenesis and Neurogenesis in MCAO Rats
LITUS treatment effectively improves motor dysfunction in MCAO rats, potentially through the regulation of microglial polarization and the promotion of angiogenesis and neurogenesis. Therefore, LITUS may represent a promising therapeutic approach for addressing motor recovery associated with ischemic stroke.
Authors
- Chao Shi (ORCID: https://orcid.org/0000-0002-4810-7603)
- Peng Wu (ORCID: https://orcid.org/0000-0003-1157-9401)
- Aidong Li (ORCID: https://orcid.org/0000-0003-3628-0393)
- Yongjie Zhu (ORCID: https://orcid.org/0000-0002-8714-2647)
- Li Luo (ORCID: https://orcid.org/0000-0002-0536-0481)
- Qingqing Meng (ORCID: https://orcid.org/0000-0002-8830-2606)
- Yao Wang (ORCID: https://orcid.org/0000-0002-5216-6411)
- Rui Li (ORCID: https://orcid.org/0000-0002-7210-8358)
- Min He (ORCID: https://orcid.org/0000-0001-6755-7872)
- Hongmei Wen (ORCID: https://orcid.org/0000-0002-0339-2498)
- Chunfang Li (ORCID: https://orcid.org/0000-0002-3927-3845)
- Xiaojing Long (ORCID: https://orcid.org/0000-0003-4455-7831)
- Xu Huang (ORCID: https://orcid.org/0000-0003-0338-4858)
- Xuewei Cao
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Sciences (CN)
- Soochow University (CN)
- Shenzhen Sixth People's Hospital (CN)
- ShenZhen People’s Hospital (CN)
- Green Technology (US)
- Shenzhen Institutes of Advanced Technology (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Ultrasound in Medicine & Biology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1016/j.ultrasmedbio.2025.05.031
- Citations
- 1
- Primary Topic
- Stroke Rehabilitation and Recovery
- Type
- article
- Field-Weighted Citation Impact
- 1.03
Funders
- Chinese Academy of Sciences