Comparison of active and dormant <i>Mycobacterium tuberculosis</i> DosR/DevR regulon polymerase chain reaction–restriction fragment length polymorphism patterns

Results suggested that the DosR regulon may have more nucleotide variations at the active stage. This study is the first to investigate the devR, devS, and dosT genes using PCR-RFLP as a cost-effective and straightforward method.

Authors

Ali Akbar Velayati (ORCID: https://orcid.org/0000-0001-9398-5838)
Parissa Farnia (ORCID: https://orcid.org/0000-0003-3676-2018)
Poopak Farnia (ORCID: https://orcid.org/0000-0003-3190-2827)
Faezeh Hamidieh (ORCID: https://orcid.org/0000-0002-0442-4754)

Institutions

Masih Daneshvari Hospital (IR)
Shahid Beheshti University of Medical Sciences (IR)

Publication Details

Journal: Laboratory Medicine
Published: 2025-06-23
DOI: https://doi.org/10.1093/labmed/lmaf046
Primary Topic: Tuberculosis Research and Epidemiology
Type: article
Field-Weighted Citation Impact: 0.00

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article

Comparison of active and dormant Mycobacterium tuberculosis DosR/DevR regulon polymerase chain reaction–restriction fragment length polymorphism patterns

Ali Akbar Velayati, Parissa Farnia, Poopak Farnia, Faezeh Hamidieh

Jun 23, 2025

Laboratory Medicine

Tuberculosis Research and Epidemiology

article

Comparison of active and dormant Mycobacterium tuberculosis DosR/DevR regulon polymerase chain reaction–restriction fragment length polymorphism patterns

Ali Akbar Velayati, Parissa Farnia, Poopak Farnia, Faezeh Hamidieh

June 23, 2025article en

Abstract

Results suggested that the DosR regulon may have more nucleotide variations at the active stage. This study is the first to investigate the devR, devS, and dosT genes using PCR-RFLP as a cost-effective and straightforward method.

Laboratory MedicineVol. 56(6)

Masih Daneshvari Hospital (IR), Shahid Beheshti University of Medical Sciences (IR)

Openalex Percentile: Top 75%

Tuberculosis Research and Epidemiology

DOI Source OpenAlex

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