Microvascular Insights Into Hyaluronic Acid Filler Dispersal Within an Artificial Model of Arterial Embolism

HA fillers behave as deformable embolic particles that disperse distally under physiologic microtubular conditions. These findings support a concurrent microembolic mechanism underlying filler-induced ischemia. Product rheology, cannula gauge, and vascular anatomy are important determinants of embolic particle behavior.

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Publication Details

Journal
Aesthetic Surgery Journal
Published
2025-07-30
DOI
https://doi.org/10.1093/asj/sjaf155
Primary Topic
Facial Rejuvenation and Surgery Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Microvascular Insights Into Hyaluronic Acid Filler Dispersal Within an Artificial Model of Arterial Embolism

Thomas J. Kean, Danny J. Soares, Alec McCarthy, Robyn D. Siperstein et al.
Aesthetic Surgery Journal
Facial Rejuvenation and Surgery Techniques
article

Microvascular Insights Into Hyaluronic Acid Filler Dispersal Within an Artificial Model of Arterial Embolism

Thomas J. Kean, Danny J. Soares, Alec McCarthy, Robyn D. Siperstein, Suzanne Trudel
article en

Abstract

HA fillers behave as deformable embolic particles that disperse distally under physiologic microtubular conditions. These findings support a concurrent microembolic mechanism underlying filler-induced ischemia. Product rheology, cannula gauge, and vascular anatomy are important determinants of embolic particle behavior.

Aesthetic Surgery JournalVol. 46(1)
University of Central Florida (US), Merz (United States) (US), Institute of Dermatology (TH)
Openalex Percentile: Top 64%
Facial Rejuvenation and Surgery Techniques
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Microvascular Insights Into Hyaluronic Acid Filler Dispersal Within an Artificial Model of Arterial Embolism — Thomas J. Kean, Danny J. Soares, et al. · Aesthetic Surgery Journal (2025) | TGRS Research Map | TGRS