Randomized Controlled Trial Comparative Study in Powered and Manual Stapler in Low Anterior Resection of Rectal Cancer

Although the PCS group showed a trend toward higher anastomotic leakage rates, the difference was not statistically significant. The interval between CRT completion and surgery emerged as a significant predictor of leakage. Further research is needed to establish optimal timing for surgery post-CRT and to determine whether stapler type influences outcomes in high-risk patients.