Oestrogen replacement combined with resistance exercise in older women with knee osteoarthritis: a randomised, double-blind, placebo-controlled clinical trial
ERT did not confer significant additive benefits to resistance exercise overall but may improve outcomes in early-stage KOA and mental health domains. These exploratory findings warrant further investigation.
Authors
- Hikaru Ooba (ORCID: https://orcid.org/0000-0002-8676-1892)
- Tomohiro Mitoma (ORCID: https://orcid.org/0000-0001-8013-0718)
- Toshiharu Mitsuhashi (ORCID: https://orcid.org/0000-0001-9940-0570)
- Yoko Sakamoto (ORCID: https://orcid.org/0009-0006-9908-6191)
- Kasumi Takahashi
- Tsunemasa Kondo
- Jota Maki (ORCID: https://orcid.org/0000-0003-4800-4249)
- Tomohiro Ikeda (ORCID: https://orcid.org/0000-0001-5350-944X)
Institutions
- Okayama University (JP)
- Okayama University Hospital (JP)
- Chugoku Central Hospital (JP)
- Okayama Rosai Hospital (JP)
Publication Details
- Journal
- Age and Ageing
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1093/ageing/afaf224
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.34