Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy

Our study established the causal linkage between autophagy and ICP, providing a potential therapeutic avenue to improve trophoblast function accounting for ICP by targeting autophagy gene TNFSF10.

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Publication Details

Journal
Biology of Reproduction
Published
2025-08-11
DOI
https://doi.org/10.1093/biolre/ioaf184
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy

Peilin Wang, Szu‐Yuan Wu, Mi Tang, Shasha Xing et al.
Biology of Reproduction
Pediatric Hepatobiliary Diseases and Treatments
article

Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy

Peilin Wang, Szu‐Yuan Wu, Mi Tang, Shasha Xing, Liling Xiong, Jianghui Cai, Xiao Yang, Jing Yang, Ling Zhang, Mengqiu Luo, Zihao Zhao, Xiaoyu Zhou, Xuejia Gong
article en

Abstract

Our study established the causal linkage between autophagy and ICP, providing a potential therapeutic avenue to improve trophoblast function accounting for ICP by targeting autophagy gene TNFSF10.

Biology of ReproductionVol. 113(6)
University of Electronic Science and Technology of China (CN), Affiliated Hospital of Southwest Medical University (CN), Chengdu Women's and Children's Central Hospital (CN)
Openalex Percentile: Top 67%
Pediatric Hepatobiliary Diseases and Treatments
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