4-Methoxylonchocarpin protects against cisplatin induced acute kidney injury via regulating ferroptosis

These findings suggest that 4ML as a promising therapeutic agent for cisplatin-induced AKI, primarily through inhibiting ferroptosis and regulating AMPK. This study provides further evidence supporting the potential of traditional Chinese medicine-derived compounds in the management of AKI.

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Publication Details

Journal
Renal Failure
Published
2025-08-12
DOI
https://doi.org/10.1080/0886022x.2025.2545941
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

4-Methoxylonchocarpin protects against cisplatin induced acute kidney injury via regulating ferroptosis

Baodong Wang, Nan Jiao, Qiong Zhang, Yuxiang Liu et al.
Renal Failure
Ferroptosis and cancer prognosis
article

4-Methoxylonchocarpin protects against cisplatin induced acute kidney injury via regulating ferroptosis

Baodong Wang, Nan Jiao, Qiong Zhang, Yuxiang Liu, Fen Zhao
article en

Abstract

These findings suggest that 4ML as a promising therapeutic agent for cisplatin-induced AKI, primarily through inhibiting ferroptosis and regulating AMPK. This study provides further evidence supporting the potential of traditional Chinese medicine-derived compounds in the management of AKI.

Renal FailureVol. 47(1)
Shanxi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 69%
Ferroptosis and cancer prognosis
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