Myocardial ischemia/reperfusion-induced glycolysis enhances damage through TRPM7 histone lactylation
This study highlighted that histone lactylation could be a potential therapeutic target for modulating TRPM7 expression and mitigating I/R injury.
Authors
- Jun Shao (ORCID: https://orcid.org/0000-0002-6493-4086)
- Yonggang Shi (ORCID: https://orcid.org/0009-0003-7681-2355)
- Guiqing Liu (ORCID: https://orcid.org/0000-0003-2913-8196)
- Jae‐Hun Yang (ORCID: https://orcid.org/0000-0003-1929-2878)
- Congcong Li (ORCID: https://orcid.org/0000-0002-9678-1440)
- Wanqi Lan
- Wu Liu (ORCID: https://orcid.org/0000-0001-5809-9785)
- Haiyan Xiang
- Shan Hu (ORCID: https://orcid.org/0000-0003-2984-5317)
- Chao Luo (ORCID: https://orcid.org/0009-0002-5490-5633)
- Yanhua Tang (ORCID: https://orcid.org/0000-0001-6567-2455)
Institutions
- Nanchang University (CN)
- Imperial College Healthcare NHS Trust (GB)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Toxicology and Applied Pharmacology
- Published
- 2025-08-10
- DOI
- https://doi.org/10.1016/j.taap.2025.117508
- Citations
- 2
- Primary Topic
- Magnesium in Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province