The novel triglyceride‒glucose-weighted adjusted waist index as a supplementary diagnostic tool for heart failure: evidence of improved reclassification beyond traditional TyG-related indices from a cross-sectional study

In the general population, the TyG-WWI is strongly, independently, and dose-dependently associated with heart failure (HF) risk. Notably, its diagnostic performance for HFs surpasses that of traditional TyG-related indices, and it has incremental value as a supplementary parameter to existing TyG-derived metrics. These findings support the use of the TyG-WWI as a promising tool for HF risk stratification with practical clinical utility. However, further validation in large-scale prospective cohorts is warranted to confirm its long-term predictive value and generalizability across diverse populations.