Discordance and shortcomings of aldosterone suppression tests in primary aldosteronism
Well-established aldosterone suppression tests for PA demonstrated substantial inconsistency, false-negative interpretations, and the inability to reliably predict lateralization outcomes in PA. Aldosterone suppression testing, using SST and CCT, lack accuracy for the diagnosis and subtyping of PA in high-risk patients.
Authors
- Chin‐Chen Chang (ORCID: https://orcid.org/0000-0002-0121-4866)
- Stéfanie Parisien‐La Salle (ORCID: https://orcid.org/0000-0001-5960-4181)
- Yen‐Hung Lin (ORCID: https://orcid.org/0000-0001-8153-1441)
- Vin‐Cent Wu (ORCID: https://orcid.org/0000-0001-7935-0991)
- Anand Vaidya (ORCID: https://orcid.org/0000-0002-0314-9252)
- Cheng‐Hsuan Tsai (ORCID: https://orcid.org/0000-0003-2859-5117)
- Jenifer M. Brown (ORCID: https://orcid.org/0000-0002-6647-639X)
- Andrew J Newman (ORCID: https://orcid.org/0000-0002-8326-1964)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
- Centre Hospitalier de l’Université de Montréal (CA)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1093/ejendo/lvaf170
- Citations
- 13
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 16.83