Immune deficiency due to SARS-CoV-2 infection in a child with GATA2-mutated AML: A case report

For AML patients with GATA2 mutation who achieve remission, SARS-CoV-2 infection may still trigger severe and persistent immunodeficiency, leading to serious infections and affecting prognosis. Therefore, early identification of GATA2 mutations and early implementation of hematopoietic stem cell transplantation are key to improving prognoses.

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Publication Details

Journal
Medicine
Published
2025-08-08
DOI
https://doi.org/10.1097/md.0000000000043734
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Immune deficiency due to SARS-CoV-2 infection in a child with GATA2-mutated AML: A case report

Linhai Yang, Chengzhu Liu, Huaju Cai, Jiale Cheng et al.
Medicine
Immunodeficiency and Autoimmune Disorders
article

Immune deficiency due to SARS-CoV-2 infection in a child with GATA2-mutated AML: A case report

Linhai Yang, Chengzhu Liu, Huaju Cai, Jiale Cheng, Anbang Wei, Ningling Wang, Kun-Long Zhang, Zhiwei Xie, Lingling Huang, Songji Tu, Yi Hong, Zhengyu Wu, Jinhua Chu
article en

Abstract

For AML patients with GATA2 mutation who achieve remission, SARS-CoV-2 infection may still trigger severe and persistent immunodeficiency, leading to serious infections and affecting prognosis. Therefore, early identification of GATA2 mutations and early implementation of hematopoietic stem cell transplantation are key to improving prognoses.

MedicineVol. 104(32)
Anhui Medical University (CN), Second Affiliated Hospital of Anhui Medical University (CN)
Good health and well-being
Openalex Percentile: Top 78%
Immunodeficiency and Autoimmune Disorders
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