HUMESS: integrating quantitative transcriptomic analysis and metabolic modeling to unveil condition-specific gene signatures
HUMESS is open source and available under GitLab https://gitlab.univ-nantes.fr/bird_pipeline_registry/humess with the complete documentation available at https://gitlab.univ-nantes.fr/bird_pipeline_registry/humess/-/wikis/Home. A zenodo archive is also available at the following DOI: https://doi.org/10.5281/zenodo.15487717. An RShiny application has been developed to facilitate the exploration and analysis of HUMESS's results. The app is available online at the following address: https://shiny-bird.univ-nantes.fr/app/shinymess but can also be installed locally, available under GitLab https://gitlab.univ-nantes.fr/pare-l/shinymess.
Authors
- Audrey Bihouée (ORCID: https://orcid.org/0000-0002-8689-2083)
- Louis Paré
- Philippe Bordron (ORCID: https://orcid.org/0000-0003-1975-0920)
- Damien Eveillard (ORCID: https://orcid.org/0000-0002-8162-7360)
- Laurent David (ORCID: https://orcid.org/0000-0003-3594-0353)
- Maxime Mahé
Institutions
- École Centrale de Nantes (FR)
- Cincinnati Children's Hospital Medical Center (US)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- The Enteric Nervous System in Gut and Brain Disorders (FR)
- Laboratoire des Sciences du Numérique de Nantes (FR)
- Institut du Thorax (FR)
- Génétique Physiologie et Systèmes d'Elevage (FR)
- University of Cincinnati (US)
- Nantes Université (FR)
Publication Details
- Journal
- Bioinformatics
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1093/bioinformatics/btaf448
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche