Reproducibility of Ki67 Haralick entropy as a prognostic marker in estrogen receptor–positive HER2-negative breast cancer
Ki67 Haralick entropy is a reproducible and robust image-derived ITH metric in ER+/HER2- BC. It demonstrated improved prognostic modeling performance compared to conventional Ki67% across 2 different DIA platforms and sampling conditions, supporting its potential for clinical implementation.
Authors
- Allan G. Rasmusson (ORCID: https://orcid.org/0000-0001-6705-6795)
- Ruta Barbora Valkiuniene
- Dovile Zilenaite-Petrulaitiene (ORCID: https://orcid.org/0000-0002-7221-2868)
- Linas Petkevičius (ORCID: https://orcid.org/0000-0003-2416-0431)
- Arvydas Laurinavičius (ORCID: https://orcid.org/0000-0001-9232-1730)
- Aida Laurinavičienė
Institutions
- Vilnius University (LT)
- Vilnius University of Applied Sciences (LT)
- Vilnius University Hospital Santariskiu Klinikos (LT)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1093/ajcp/aqaf081
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lietuvos Mokslo Taryba