Changing from the CKD-EPI to the EKFC creatinine equation to estimate glomerular filtration rate in adults in a Northern European health system
Adopting the EKFC equation in this Northern European health system would modestly lower eGFR estimates, increasing the prevalence of moderate/severe CKD and affecting clinical classification and decisions. eGFR by both equations strongly predicted outcomes, but individuals reclassified to a lower eGFR category by EKFC did not have consistent associations across outcomes.
Authors
- Anne‐Laure Faucon (ORCID: https://orcid.org/0000-0001-6716-1157)
- Antoine Créon (ORCID: https://orcid.org/0009-0006-6498-0257)
- Edouard L. Fu (ORCID: https://orcid.org/0000-0002-9698-6825)
- Andrew S. Levey (ORCID: https://orcid.org/0000-0003-1491-501X)
- Pierre Delanaye (ORCID: https://orcid.org/0000-0002-1480-5761)
- Juan Jesús Carrero (ORCID: https://orcid.org/0000-0003-4763-2024)
- Lesley A. Inker (ORCID: https://orcid.org/0000-0003-2820-9482)
- William A. Russel
- Alberto Ortíz (ORCID: https://orcid.org/0000-0002-9805-9523)
- Pim Bouwmans (ORCID: https://orcid.org/0000-0001-9977-8637)
- Hans Pottel (ORCID: https://orcid.org/0000-0003-0074-8919)
- Aurora Caldinelli (ORCID: https://orcid.org/0009-0009-6019-9342)
Institutions
- Tufts Medical Center (US)
- University of Liège (BE)
- Leiden University Medical Center (NL)
- Karolinska Institutet (SE)
- Maastricht University (NL)
- Centre Hospitalier Universitaire de Nîmes (FR)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Primary Health Care (QA)
- Centre Hospitalier Universitaire de Liège (BE)
- Department of Public Health (MM)
- Universidad Autónoma de Madrid (ES)
- Université de Nîmes (FR)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1093/ndt/gfaf148
- Citations
- 2
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Nierstichting
- Karolinska Institutet
- Vetenskapsrådet
- National Institutes of Health