A retrospective study of clinical characteristics and steroid therapy in immune checkpoint inhibitor-mediated hepatitis
Female gender, younger age (<45 years), HCC, and gastric cancer are independent risk factors for IMH. Younger patients are more likely to develop severe IMH. Glucocorticoid therapy is beneficial, particularly in grade 3-4 IMH. Early detection, prompt intervention, and tailored management strategies may help mitigate progression and improve outcomes.
Authors
- Chuan Jiang (ORCID: https://orcid.org/0000-0002-1601-6854)
- Wenting Peng (ORCID: https://orcid.org/0000-0003-2342-4263)
- Shifang Peng (ORCID: https://orcid.org/0000-0001-5923-4029)
- Ying Li (ORCID: https://orcid.org/0000-0002-4286-876X)
- Lei Fu (ORCID: https://orcid.org/0000-0001-7550-1254)
- Fei-Lan Yang
- Huimin Gu
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Therapeutic Advances in Medical Oncology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/17588359251357685
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province