The relationship between the urokinase-type plasminogen activator gene Pro141Leu polymorphism and patients with prostate cancer

This is the first study to investigate the association between the rs2227564 polymorphism and prostate cancer. Although the urokinase-type plasminogen activator gene Pro141Leu polymorphism has been reported to be a risk factor for some cancers, our findings suggest that the urokinase-type plasminogen activator gene Pro141Leu polymorphism is not an important genetic risk factor for prostate cancer.

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Publication Details

Journal
Revista da Associação Médica Brasileira
Published
2025-01-01
DOI
https://doi.org/10.1590/1806-9282.20250097
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
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article

The relationship between the urokinase-type plasminogen activator gene Pro141Leu polymorphism and patients with prostate cancer

Murat Bozlu, Cemil Gülüm, Rojda Tanrıverdi, Pelin Eroğlu
Revista da Associação Médica Brasileira
Protease and Inhibitor Mechanisms
article

The relationship between the urokinase-type plasminogen activator gene Pro141Leu polymorphism and patients with prostate cancer

Murat Bozlu, Cemil Gülüm, Rojda Tanrıverdi, Pelin Eroğlu
article en

Abstract

This is the first study to investigate the association between the rs2227564 polymorphism and prostate cancer. Although the urokinase-type plasminogen activator gene Pro141Leu polymorphism has been reported to be a risk factor for some cancers, our findings suggest that the urokinase-type plasminogen activator gene Pro141Leu polymorphism is not an important genetic risk factor for prostate cancer.

Revista da Associação Médica BrasileiraVol. 71(7)
Mersin Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 74%
Protease and Inhibitor Mechanisms
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