Diffuse and Strong TTF-1 Expression Predicts Response to Pemetrexed-Based Immunochemotherapy in Advanced Lung Adenocarcinoma

Diffuse and strong TTF-1 positivity may be useful for the predictive factor for pemetrexed-based immunochemotherapy. TTF-1 staining may be desirable to develop a more optimal immunochemotherapy for lung adenocarcinoma.

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Publication Details

Journal
Cancer Management and Research
Published
2025-08-01
DOI
https://doi.org/10.2147/cmar.s520436
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Diffuse and Strong TTF-1 Expression Predicts Response to Pemetrexed-Based Immunochemotherapy in Advanced Lung Adenocarcinoma

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Cancer Management and Research
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Diffuse and Strong TTF-1 Expression Predicts Response to Pemetrexed-Based Immunochemotherapy in Advanced Lung Adenocarcinoma

Motoko Tachihara, Jun Yamada, Natsuhiko Iwamoto, Naoe Jimbo, Yukihisa Hatakeyama, Masahiro Katsurada, Kanoko Matsumura, Keiko Okuno, Tatsunori Kiriu, Kyosuke Nakata, Nanami Yamasaki
article en

Abstract

Diffuse and strong TTF-1 positivity may be useful for the predictive factor for pemetrexed-based immunochemotherapy. TTF-1 staining may be desirable to develop a more optimal immunochemotherapy for lung adenocarcinoma.

Cancer Management and ResearchVol. Volume 17
Tambov State Technical University (RU), Kobe University Hospital (JP), Hyogo Prefectural Awaji Medical Center (JP), Akashi Medical Center (JP), Takatsuki General Hospital (JP), Kobe University (JP)
Good health and well-being
Openalex Percentile: Top 69%
Lung Cancer Treatments and Mutations
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