Comparative genomics reveals the genetic diversity and plasticity of <i>Clostridium tertium</i>
Clostridium tertium exhibited extensive genetic diversity and genome plasticity, probably driven by MGE-mediated HGT, defense mechanisms of CRISPR-Cas systems, and functional adaptation related to virulence and resistance. These traits may underlie its ability to colonize diverse environments and acquire pathogenicity and resistance.
Authors
- Zhengchang Liao (ORCID: https://orcid.org/0000-0003-4385-2871)
- Yunming Qing
- Xian Zhang (ORCID: https://orcid.org/0000-0003-4079-9470)
- Di An (ORCID: https://orcid.org/0000-0001-6171-7791)
- Qin Zhu
- Ying Zeng (ORCID: https://orcid.org/0000-0002-1680-6610)
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1093/jambio/lxaf201
- Citations
- 1
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 1.40