Obesity Associated With Symptomatic Remission in Clozapine-Treated Individuals With Treatment-Resistant Schizophrenia
Our study found that obesity was associated with remission in TRS patients on clozapine. This lends support to the metabolic threshold for clozapine. Further investigations are needed to study the mechanisms underpinning weight gain and clozapine efficacy.
Authors
- Jie Yin Yee (ORCID: https://orcid.org/0000-0002-4346-445X)
- Yuen Mei See (ORCID: https://orcid.org/0000-0002-2022-463X)
- Daniel R. Chang
- Jimmy Lee (ORCID: https://orcid.org/0000-0002-7724-7445)
- Claire Law (ORCID: https://orcid.org/0000-0003-1210-4635)
Institutions
- Nanyang Technological University (SG)
- Institute of Mental Health (SG)
Publication Details
- Journal
- Journal of Clinical Psychopharmacology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1097/jcp.0000000000002048
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00