Treatment of achalasia led to normalisation of energy metabolism and proteosynthesis dependent on the pool of circulating amino acids; metabolomic monitoring and body composition analysis on insufficient nutrition
Our observations provide complex insight into the metabolic shifts after successful treatment of achalasia that is directly related to the changes in the body composition. The metabolic alterations were not detectable through standard biochemical tests suggesting that conventional diagnostics may not fully reflect the metabolic condition of patients with achalasia.
Authors
- Michal Demeter
- Peter Bánovčin (ORCID: https://orcid.org/0000-0001-6694-9364)
- Martin Kertys (ORCID: https://orcid.org/0000-0002-1095-6810)
- Diana Vážanová (ORCID: https://orcid.org/0009-0008-9606-117X)
- Lenka Nosáková
- Ján Lehotský (ORCID: https://orcid.org/0000-0002-2408-5745)
- Martin Ďuríček (ORCID: https://orcid.org/0000-0002-0754-4532)
- Erika Halášová (ORCID: https://orcid.org/0000-0003-2458-1391)
- Eva Baranovičová (ORCID: https://orcid.org/0000-0003-1357-9368)
- Martin Vojtko
Institutions
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1007/s11306-025-02303-6
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Univerzita Komenského v Bratislave
- Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky
- Agentúra na Podporu Výskumu a Vývoja
- Vedecká Grantová Agentúra MŠVVaŠ SR a SAV