Treatment Patterns of Patients With Mitral Valve Disease and Critical Neo‐LVOT Obstruction

Patients with severe MV disease at high-risk for LVOTO (LVOT < 150 mm<sup>2</sup>) after TMVR were overwhelmingly female and were most frequently assigned to medical therapy. Patients with severe MAC had higher rates of death. Treatment allocation was not independently associated with mortality. Novel transcatheter therapies are needed to definitively treat this high-risk population.

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Publication Details

Journal
Catheterization and Cardiovascular Interventions
Published
2025-08-12
DOI
https://doi.org/10.1002/ccd.70091
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment Patterns of Patients With Mitral Valve Disease and Critical Neo‐LVOT Obstruction

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Catheterization and Cardiovascular Interventions
Cardiac Valve Diseases and Treatments
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Treatment Patterns of Patients With Mitral Valve Disease and Critical Neo‐LVOT Obstruction

William W. O’Neill, Georgi Fram, Pedro Engel Gonzalez, Adnan Halboni, Pedro Villablanca, Dee Dee Wang, Brian O’Neill, Gennaro Giustino, Tiberio Frisoli, Jonathan Fang
article en

Abstract

Patients with severe MV disease at high-risk for LVOTO (LVOT < 150 mm<sup>2</sup>) after TMVR were overwhelmingly female and were most frequently assigned to medical therapy. Patients with severe MAC had higher rates of death. Treatment allocation was not independently associated with mortality. Novel transcatheter therapies are needed to definitively treat this high-risk population.

Catheterization and Cardiovascular InterventionsVol. 106(4)
Henry Ford Health System (US), Morristown Medical Center (US), Naples Anesthesia & Physician Associates (US), National Heart Centre Singapore (SG), Atlantic Health System (US)
Openalex Percentile: Top 68%
Cardiac Valve Diseases and Treatments
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