LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy
Our findings highlight lncRNA GTF3C1 as a critical regulator of autophagy in diabetic corneal nerves, offering a potential diagnostic and therapeutic target for DCN. This study provides molecular insights into the pathogenesis of DCN and lays the groundwork for future clinical strategies.
Authors
- Jianzhang Hu (ORCID: https://orcid.org/0000-0003-0610-7856)
- Yuyang Deng
- Woei‐Luen Chen (ORCID: https://orcid.org/0000-0002-3607-789X)
- Li Wang (ORCID: https://orcid.org/0000-0002-4007-6654)
- Danling Liao
- S. Wei (ORCID: https://orcid.org/0009-0006-7341-6244)
Institutions
- Fujian Medical University (CN)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Union Hospital (CN)
Publication Details
- Journal
- Eye and Vision
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s40662-025-00448-y
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00