Role of overnight oximetry in assessing the severity of obstructive sleep apnoea in children with Down syndrome: a dual-centre study
Raised ODI3 and ODI4 predict moderate and severe OSA in children with DS with moderate specificity/sensitivity and have a low sensitivity for detecting mild OSA. The poor predictive performance of oximetry reflects the multifactorial nature of sleep disordered breathing in children with DS. We recommend oximetry is not used for diagnosis of OSA in DS and CRP/polysomnography should be used.
Authors
- Paul Burns (ORCID: https://orcid.org/0000-0001-5113-5923)
- Anna Selby (ORCID: https://orcid.org/0000-0003-4044-7125)
- Neil Gibson (ORCID: https://orcid.org/0000-0003-0136-1062)
- Elise Buchan
- Hazel Jean Evans (ORCID: https://orcid.org/0000-0001-9366-556X)
- Hannah Vennard (ORCID: https://orcid.org/0009-0008-7291-6372)
- Jonathan James (ORCID: https://orcid.org/0000-0002-8206-1637)
- Rebecca Lennon
- David Young (ORCID: https://orcid.org/0000-0002-3652-0513)
- Martin Samuels (ORCID: https://orcid.org/0000-0002-9811-8335)
- Ross Langley (ORCID: https://orcid.org/0009-0007-6069-1914)
- T. J. Wilkinson
- Menaga Ananthamoorthy
Institutions
- University of Strathclyde (GB)
- Great Ormond Street Hospital (GB)
- Royal Hospital for Children (GB)
- Southampton Children's Hospital (GB)
- University of Southampton (GB)
- University College London (GB)
Publication Details
- Journal
- Archives of Disease in Childhood
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1136/archdischild-2025-328767
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00