DNA 5-Hydroxymethylcytosine Landscape and Transcriptional Profile Highlight the TUBB4B-Mediated Th17/Th1/Treg Imbalance in Behçet's Uveitis
This study underscores the pivotal role of pathogen-induced immune dysregulation in BU development and identifies TUBB4B as a potential therapeutic target for the study on prevention and treatment of this disease.
Authors
- Peizeng Yang (ORCID: https://orcid.org/0000-0002-2647-6619)
- Wanyun Zhang
- Xiang Luo
- Guannan Su (ORCID: https://orcid.org/0000-0001-6411-3643)
- Zhou Qian (ORCID: https://orcid.org/0000-0003-1938-5222)
- Ziqian Huang
- Yujie Lai (ORCID: https://orcid.org/0000-0002-6006-1791)
- Yanlin Pu
- Pei Zhang (ORCID: https://orcid.org/0000-0002-5442-2781)
- Yinan Zhang (ORCID: https://orcid.org/0000-0003-3979-4234)
- Yang Deng (ORCID: https://orcid.org/0000-0002-4803-9014)
- Zhijun Chen (ORCID: https://orcid.org/0009-0001-8258-0736)
- Yan Ji
Institutions
- People's Hospital of Bishan District (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1167/iovs.66.11.28
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Chongqing Science and Technology Commission