Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis

Nearly half of the patients experienced ≥ 1 irAEs, of which one-third severe. Females experienced more irAEs than males, above all due to a higher incidence of grade 1 irAEs. Only about half of the irAEs were reported as coded diagnosis. Further prospective studies on irAEs are warranted using structured documentation.

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Publication Details

Journal
BMC Cancer
Published
2025-08-11
DOI
https://doi.org/10.1186/s12885-025-14733-5
Citations
4
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
4.18
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article

Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis

Dirk Lehnick, Balthasar L. Hug, Chloé Sieber, Lauris Annatha Mariam Auch
4 citations
BMC Cancer
Cancer Immunotherapy and Biomarkers
4.18
article

Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis

Dirk Lehnick, Balthasar L. Hug, Chloé Sieber, Lauris Annatha Mariam Auch
article en
4 citations

Abstract

Nearly half of the patients experienced ≥ 1 irAEs, of which one-third severe. Females experienced more irAEs than males, above all due to a higher incidence of grade 1 irAEs. Only about half of the irAEs were reported as coded diagnosis. Further prospective studies on irAEs are warranted using structured documentation.

BMC CancerVol. 25(1)
University of Lucerne (CH)
Good health and well-being
Openalex Percentile: Top 5%
Cancer Immunotherapy and Biomarkers
4.18
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