Two new cadinane-type sesquiterpene glycosides from <i>Dendrobium findleyanum</i>
Two novel and two previously identified cadinane-type sesquiterpene glycosides, findleyanosides E-F (<b>1</b>-<b>2</b>), balanoindicoside B (<b>3</b>) and pumilaside C (<b>4</b>), were extracted from the <i>Dendrobium findleyanum</i> stems. The establishment of structures was mainly conducted <i>via</i> spectroscopic techniques and by comparing with literature data. Electronic circular dichroism (ECD) computations helped determine the absolute configuration of the novel molecules. All molecules exhibited moderate cytotoxic effects against A-549 human tumour cell lines, with IC<sub>50</sub> values of 15.52, 17.68, 13.85 and 16.64 <i>μ</i>M, respectively.
Authors
- Dan Yang (ORCID: https://orcid.org/0000-0002-2680-6315)
- Zhi‐Qing Lin
- Zhong‐Quan Cheng
Institutions
- Guangdong Medical College (CN)
- Guangzhou Vocational College of Science and Technology (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1080/14786419.2025.2545981
- Primary Topic
- Biological and pharmacological studies of plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00