Optimization of degradation conditions and elucidation of novel biodegradation pathways for sulfamonomethoxine by a novel <i>Bacillus</i> strain
The discovery of a new <i>Bacillus</i> sp., strain DLY-11, from aerobically composted swine manure offers significant environmental benefits by efficiently degrading 98.8% of 20 mg/L sulfamonomethoxine (SMM) within 48 hours under optimal conditions (5% inoculation volume, 59.1°C, pH 7.10, 0.45 g/L MgSO4). This strain introduces a new tool for reducing SMM antibiotic pollution and reveals a novel degradation pathway, enhancing our understanding of SMM biodegradation mechanisms and supporting targeted bioremediation strategies.
Authors
- Chunyan Chen (ORCID: https://orcid.org/0000-0001-9220-4569)
- Yuwan Pang
- Zebin Wei (ORCID: https://orcid.org/0000-0003-3321-2598)
- Qianyi Cai (ORCID: https://orcid.org/0009-0005-4650-8437)
- Zifeng Luo
- Hongxing Tu
- Charles R. Long (ORCID: https://orcid.org/0000-0003-4330-0786)
- Xiujuan Wang (ORCID: https://orcid.org/0000-0003-1520-9053)
- Xiaojun Lin
- Jinrong Qiu (ORCID: https://orcid.org/0000-0003-3602-5106)
- Jingtong Li
Institutions
- South China Agricultural University (CN)
- Jinan University (CN)
- Yangtze University (CN)
- Guangdong Academy of Agricultural Sciences (CN)
- Guangzhou Municipal Engineering Design and Research Institute (CN)
- State Key Joint Laboratory of Environment Simulation and Pollution Control (CN)
- South China Institute Of Environmental Sciences (CN)
- Guangdong Province Environmental Monitoring Center (CN)
Publication Details
- Journal
- Applied and Environmental Microbiology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1128/aem.01329-25
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation