LC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacterales
Our models demonstrate the ability to distinguish CPE from non-CPE in under 7 h using metabolite biomarkers, showing potential for the development of a targeted diagnostic assay.
Authors
- Stephen James Fowler (ORCID: https://orcid.org/0000-0002-4524-1663)
- Waqar Ahmed (ORCID: https://orcid.org/0000-0003-1490-6391)
- Breanna Dixon (ORCID: https://orcid.org/0000-0002-4286-1410)
- Tim Felton (ORCID: https://orcid.org/0000-0001-6868-6633)
- Drupad K. Trivedi (ORCID: https://orcid.org/0000-0001-7969-0195)
Institutions
- University of Manchester (GB)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1007/s11306-025-02300-9
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- North Bristol NHS Trust
- Manchester Biomedical Research Centre
- Biotechnology and Biological Sciences Research Council