Is it necessary to request testing for antibodies against extractable nuclear antigens in case of antinuclear antibody negativity?

The results of our study support proposals to reduce ENA testing after a negative ANA test and gradually increase it after a positive test or clinical indication. It will eliminate inaccurate test requests, expenditures, and unnecessary patient assessments.

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Publication Details

Journal
Scandinavian Journal of Clinical and Laboratory Investigation
Published
2025-07-04
DOI
https://doi.org/10.1080/00365513.2025.2547049
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
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article

Is it necessary to request testing for antibodies against extractable nuclear antigens in case of antinuclear antibody negativity?

Bedia Dinç, Emrah Salman
Scandinavian Journal of Clinical and Laboratory Investigation
Monoclonal and Polyclonal Antibodies Research
article

Is it necessary to request testing for antibodies against extractable nuclear antigens in case of antinuclear antibody negativity?

Bedia Dinç, Emrah Salman
article en

Abstract

The results of our study support proposals to reduce ENA testing after a negative ANA test and gradually increase it after a positive test or clinical indication. It will eliminate inaccurate test requests, expenditures, and unnecessary patient assessments.

Scandinavian Journal of Clinical and Laboratory InvestigationVol. 85(5)
Bilkent University (TR), Başkent University Hospital (TR), Ankara Bilkent City Hospital (TR)
Good health and well-being
Openalex Percentile: Top 71%
Monoclonal and Polyclonal Antibodies Research
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