Development, validation, and preliminary phenotypic characterization of a <i>Col6a3</i> knockout mouse model targeting exon 3

In summary, we performed the validation and preliminary phenotypic characterization of a novel Col6a3 knockout mouse model that could be further characterized and used to study COL6A3 biology and model collagen VI-associated diseases.

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Publication Details

Journal
Animal Models and Experimental Medicine
Published
2025-08-12
DOI
https://doi.org/10.1002/ame2.70063
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Development, validation, and preliminary phenotypic characterization of a Col6a3 knockout mouse model targeting exon 3

Roger Lecomte, Xavier Roucou, Maude Lévesque, Jean‐François Jacques et al.
Animal Models and Experimental Medicine
Muscle Physiology and Disorders
article

Development, validation, and preliminary phenotypic characterization of a Col6a3 knockout mouse model targeting exon 3

Roger Lecomte, Xavier Roucou, Maude Lévesque, Jean‐François Jacques, Brian T. Gaudette, François‐Michel Boisvert, Maxime Caron, Jonathan Beaudoin, Jean‐Philippe Brosseau, Otman Sarrhini, Harsimran Sidhu, Michel ElChoueiry, Dominique Lévesque
article en

Abstract

In summary, we performed the validation and preliminary phenotypic characterization of a novel Col6a3 knockout mouse model that could be further characterized and used to study COL6A3 biology and model collagen VI-associated diseases.

Animal Models and Experimental MedicineVol. 8(10)
Université de Sherbrooke (CA), Centre Hospitalier Universitaire de Sherbrooke (CA)
Université de Sherbrooke, Fonds de Recherche du Québec - Santé
Openalex Percentile: Top 82%
Muscle Physiology and Disorders
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