Prolonged paralysis following mivacurium administration in a pediatric patient with previously undiagnosed pseudocholinesterase deficiency: a case report
This is a case report of pseudocholinesterase deficiency in a 24-month-old child undergoing minor surgery. Quantitative neuromuscular monitoring should be used routinely to recognize prolonged muscle relaxation. If the diagnosis of pseudocholinesterase deficiency is confirmed, the patient should be given information about the disorder, the associated risks, inheritance and the need for testing in other family members.
Authors
- Jens H. Westhoff (ORCID: https://orcid.org/0000-0002-9837-9383)
- Felix C. F. Schmitt (ORCID: https://orcid.org/0000-0001-6464-6191)
- Fabian Ruping
- Aleksandar R. Zivkovic (ORCID: https://orcid.org/0000-0003-0757-8895)
- Davut Deniz Uzun (ORCID: https://orcid.org/0000-0002-0559-8684)
- Markus A. Weigand
- Katharina Wildenberg
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Heidelberg University (US)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s12887-025-05996-9
- Citations
- 1
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.39