TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation
Our results are consistent with tumor suppressor role of TET1 gene in lung adenocarcinoma cells (H441, H1975) and reveal its possible role in activating antitumor immunity.
Authors
- Andrew T. Rajczewski (ORCID: https://orcid.org/0000-0002-5119-8075)
- Monica Kruk (ORCID: https://orcid.org/0009-0005-6973-3207)
- Brian L. Ruis (ORCID: https://orcid.org/0000-0003-3461-2147)
- Natalia Tretyakova (ORCID: https://orcid.org/0000-0002-0621-6860)
- Abdur Rahim (ORCID: https://orcid.org/0000-0001-5841-0879)
Institutions
- University of Minnesota (US)
Publication Details
- Journal
- Epigenetics & Chromatin
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s13072-025-00617-2
- Citations
- 6
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- University of Minnesota
- National Institutes of Health