Therapeutic application of a jumbo bacteriophage against metallo-β-lactamase producing Pseudomonas aeruginosa clinical isolates
The newly reported Phikzvirus jumbo phage AttikonH10 demonstrated a broad host range, strong lytic activity and synergistic effects with amikacin against MBL-PA isolates making it a candidate for phage therapy.
Authors
- Dimitrios Skliros (ORCID: https://orcid.org/0000-0001-9753-2510)
- Emmanouil Flemetakis (ORCID: https://orcid.org/0000-0003-2530-9592)
- Marios G. Kostakis (ORCID: https://orcid.org/0000-0001-7775-4634)
- Ņikita Zrelovs (ORCID: https://orcid.org/0000-0001-7429-5962)
- Νikolaos S. Τhomaidis (ORCID: https://orcid.org/0000-0002-4624-4735)
- Paschalis Paranos (ORCID: https://orcid.org/0000-0003-1934-8691)
- Joseph Meletiadis (ORCID: https://orcid.org/0000-0002-8869-1509)
- Panagiota‐Christina Georgiou
- Andris Kazāks (ORCID: https://orcid.org/0000-0003-4964-0984)
- Karina Svanberga (ORCID: https://orcid.org/0009-0002-8691-1499)
Institutions
- Agricultural University of Athens (GR)
- Latvian Biomedical Research and Study Centre (LV)
- National and Kapodistrian University of Athens (GR)
- University General Hospital Attikon (GR)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s12929-025-01169-z
- Citations
- 2
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 3.43
Funders
- Hellenic Foundation for Research and Innovation