The role of indocyanine green in the diagnosis of biliary atresia: A word of caution

Indocyanine green (ICG) fluorescence imaging has emerged as a potential tool in evaluating biliary atresia, offering real-time visualisation of hepatobiliary excretion. Following intravenous administration, ICG is taken up by hepatocytes and excreted into bile, allowing assessment of biliary patency. In biliary atresia, absent or delayed fluorescence in the intestine may suggest obstruction. However, its diagnostic utility should be used with caution. We present a case highlighting a potential flaw in using ICG to diagnose biliary atresia.

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Publication Details

Journal
BMJ Case Reports
Published
2025-08-01
DOI
https://doi.org/10.1136/bcr-2025-266941
Citations
1
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
2.01
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article

The role of indocyanine green in the diagnosis of biliary atresia: A word of caution

Yousef El‐Gohary, Anna White, Melissa Suh, Abdalla Zarroug et al.
1 citations
BMJ Case Reports
Pediatric Hepatobiliary Diseases and Treatments
2.01
article

The role of indocyanine green in the diagnosis of biliary atresia: A word of caution

Yousef El‐Gohary, Anna White, Melissa Suh, Abdalla Zarroug, Robert A Cusick
article en
1 citations

Abstract

Indocyanine green (ICG) fluorescence imaging has emerged as a potential tool in evaluating biliary atresia, offering real-time visualisation of hepatobiliary excretion. Following intravenous administration, ICG is taken up by hepatocytes and excreted into bile, allowing assessment of biliary patency. In biliary atresia, absent or delayed fluorescence in the intestine may suggest obstruction. However, its diagnostic utility should be used with caution. We present a case highlighting a potential flaw in using ICG to diagnose biliary atresia.

BMJ Case ReportsVol. 18(8)
University of Missouri Hospital (US), Children's Hospital & Medical Center (US), University of Nebraska Medical Center (US)
Openalex Percentile: Top 13%
Pediatric Hepatobiliary Diseases and Treatments
2.01
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The role of indocyanine green in the diagnosis of biliary atresia: A word of caution — Yousef El‐Gohary, Anna White, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS