A model‐based cost‐effectiveness estimates of hormonal therapy in Indian children with infantile epileptic spasms syndrome
This study looked at two first-line treatment options, that is, ACTH and oral prednisolone, for infantile epileptic spasms syndrome (IESS) at a referral pediatric center in North India. We found that ACTH was more effective than oral prednisolone for epileptic spasm cessation and improved health-related quality of life in the short term. Although ACTH costs more, it was found to be a cost-effective option. These findings can help families and clinicians make better treatment choices based on both health benefits and costs.
Authors
- Jitendra Kumar Sahu (ORCID: https://orcid.org/0000-0001-5194-9951)
- Nagita Devi
- Saroj Kundan Bharti (ORCID: https://orcid.org/0000-0003-4221-0025)
- Priyanka Madaan (ORCID: https://orcid.org/0000-0002-8526-4691)
- Dipika Bansal (ORCID: https://orcid.org/0000-0003-4520-3293)
Institutions
- National Institute of Pharmaceutical Education and Research - Ahmedabad (IN)
- National Institute of Pharmaceutical Education and Research (IN)
- Post Graduate Institute of Medical Education and Research (IN)
- Punjab Engineering College (IN)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1002/epi4.70106
- Citations
- 2
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 6.26
Funders
- Postgraduate Institute of Medical Education and Research, Chandigarh
- National Institute of Pharmaceutical Education and Research, Raebareli