Unveiling the role of coagulation-related genes in acute myeloid leukemia prognosis and immune microenvironment through machine learning
Our study demonstrates that coagulation-related genes play a crucial role in the molecular characteristics, prognostic assessment, and immune modulation in AML. MMP7 and F12 are highlighted as potential biomarkers that could aid in optimizing the diagnosis and treatment strategies for AML. These findings offer new insights into personalized therapies for AML.
Authors
- Siyue Ma (ORCID: https://orcid.org/0009-0005-9905-8476)
- Liyun Ji (ORCID: https://orcid.org/0000-0002-5529-577X)
- Yanxia Yang (ORCID: https://orcid.org/0000-0002-8736-8275)
Institutions
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s40001-025-02975-9
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00