Practical aspects of antiplatelet therapy individualization among patients undergoing PCI for ACS and CCS. The joint expert opinion of the Working Group on Cardiovascular Pharmacotherapy and the Association of Cardiovascular Interventions of the PCS
Dual antiplatelet therapy remains the cornerstone of medical therapy among patients undergoing percutaneous coronary interventions for acute coronary syndrome or chronic coronary syndromes. Dual antiplatelet therapy is instrumental in reducing the risk of thrombotic events. However, antiplatelet agents increase the risk of bleeding. The current approach has therefore focused on assessment of individual risk factors and turned to tailor-made therapies rather than a "one-fitsall" approach. The goal of the present document is to overview the currently available antiplatelet strategies post percutaneous coronary interventions, with particular focus on patients' bleeding and ischemic risk factors as well as comorbidities and varied clinical scenarios, including patients at advanced age, patients with chronic kidney disease, diabetes, cancer, extreme body weight, and patients undergoing complex coronary procedures.
Authors
- Marcin Grabowski (ORCID: https://orcid.org/0000-0003-3306-0301)
- Przemysław Leszek (ORCID: https://orcid.org/0000-0003-4529-2687)
- Michał Hawranek (ORCID: https://orcid.org/0000-0002-8061-9975)
- Iwona Gorczyca−Michta (ORCID: https://orcid.org/0000-0002-7619-8426)
- Krzysztof J. Filipiak (ORCID: https://orcid.org/0000-0002-6563-0877)
- Marcin Wełnicki (ORCID: https://orcid.org/0000-0002-7454-521X)
- Marek Grygier (ORCID: https://orcid.org/0000-0002-1134-7099)
- Karolina Gumiężna (ORCID: https://orcid.org/0000-0002-3423-9832)
- Filip M. Szymański (ORCID: https://orcid.org/0000-0002-2638-7894)
- Mariusz Tomaniak (ORCID: https://orcid.org/0000-0001-8289-1393)
- Agnieszka Kapłon‐Cieślicka (ORCID: https://orcid.org/0000-0003-2020-3027)
- Beata Wożakowska−Kapłon (ORCID: https://orcid.org/0000-0003-1409-4362)
- Artur Mamcarz (ORCID: https://orcid.org/0000-0002-9569-1486)
- Marcin Barylski (ORCID: https://orcid.org/0000-0001-7245-9724)
- Jarosław D. Kasprzak (ORCID: https://orcid.org/0000-0002-5850-8187)
- Zenon Huczek (ORCID: https://orcid.org/0000-0002-5912-2649)
Institutions
- Poznan University of Medical Sciences (PL)
- Medical University of Silesia (PL)
- Jan Kochanowski University (PL)
- Medical University of Warsaw (PL)
- Medical University of Lodz (PL)
- Silesian Center for Heart Disease (PL)
- Institute of Cardiology (PL)
- Cardinal Stefan Wyszynski University in Warsaw (PL)
Publication Details
- Journal
- Kardiologia Polska
- Published
- 2025-08-04
- DOI
- https://doi.org/10.33963/v.phj.107838
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00