Host–Microbe Multiomic Profiling Predicts Mortality in Sepsis
Taken together, our findings provide a conceptual advance in the understanding of host and microbial factors associated with mortality in critical illness and demonstrate a new approach to mortality prediction in sepsis.
Authors
- Charles Langelier (ORCID: https://orcid.org/0000-0002-6708-4646)
- Emily Lydon (ORCID: https://orcid.org/0000-0003-3510-6254)
- Lucile Neyton (ORCID: https://orcid.org/0000-0003-1273-2228)
- Carolyn M. Hendrickson (ORCID: https://orcid.org/0000-0003-4662-2385)
- Eran Mick (ORCID: https://orcid.org/0000-0002-7299-808X)
- Joseph L. DeRisi (ORCID: https://orcid.org/0000-0002-4611-9205)
- Paula Hayakawa Serpa
- Pratik Sinha (ORCID: https://orcid.org/0000-0003-3751-9079)
- Michael A. Matthay (ORCID: https://orcid.org/0000-0003-3039-8155)
- Samantha Hao (ORCID: https://orcid.org/0000-0002-4349-8131)
- Antonio Gómez
- Carolyn S. Calfee (ORCID: https://orcid.org/0000-0001-9208-6865)
- Kathleen D. Liu (ORCID: https://orcid.org/0000-0003-4891-8649)
- Natasha Spottiswoode (ORCID: https://orcid.org/0000-0001-6157-3716)
- Katrina Kalantar (ORCID: https://orcid.org/0000-0003-0281-4625)
- Kirsten N. Kangelaris (ORCID: https://orcid.org/0000-0001-8152-994X)
- Rithwik Narendra (ORCID: https://orcid.org/0000-0003-1292-1336)
- Saharai Caldera (ORCID: https://orcid.org/0000-0001-5057-9186)
Institutions
- San Francisco General Hospital (US)
- City College of San Francisco (US)
- Palo Alto University (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- Pediatric Nephrology of Alabama (US)
- Office of Infectious Diseases (US)
- Pulmonary and Allergy Associates (US)
- Chan Zuckerberg Initiative (United States) (US)
- University of San Francisco (US)
- Stanford University (US)
Publication Details
- Journal
- American Journal of Respiratory and Critical Care Medicine
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1164/rccm.202410-1996oc
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71