Surgical treatment for postpneumonectomy syndrome

Postpneumonectomy syndrome (PPS) is a rare complication after pneumonectomy characterised by severe mediastinal shift leading to airway compression and respiratory distress. We present a case of a woman in her mid-40s who developed PPS following a right pneumonectomy for bronchial mucoepidermoid carcinoma. Surgical treatment of PPS had not previously been performed in Denmark by Danish surgeons, which is why we consulted with a British surgeon. The surgery was performed in Denmark.The procedure resulted in immediate respiratory improvement, and the patient was discharged 22 days postoperatively. Follow-up demonstrated sustained airway patency and no signs of cancer recurrence. This case highlights the feasibility and effectiveness of surgical management of PPS in centres with limited prior experience and supports mediastinal repositioning with prosthetic implants as a viable treatment option in severe cases.

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Publication Details

Journal
BMJ Case Reports
Published
2025-08-01
DOI
https://doi.org/10.1136/bcr-2025-266605
Primary Topic
Tracheal and airway disorders
Type
article
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article

Surgical treatment for postpneumonectomy syndrome

Thomas Decker Christensen, Thomas Kjærgaard, Anette Hoejsgaard, Maninder Kalkat et al.
BMJ Case Reports
Tracheal and airway disorders
article

Surgical treatment for postpneumonectomy syndrome

Thomas Decker Christensen, Thomas Kjærgaard, Anette Hoejsgaard, Maninder Kalkat, Nikolaj Vestergaard Carlsen
article en

Abstract

Postpneumonectomy syndrome (PPS) is a rare complication after pneumonectomy characterised by severe mediastinal shift leading to airway compression and respiratory distress. We present a case of a woman in her mid-40s who developed PPS following a right pneumonectomy for bronchial mucoepidermoid carcinoma. Surgical treatment of PPS had not previously been performed in Denmark by Danish surgeons, which is why we consulted with a British surgeon. The surgery was performed in Denmark.The procedure resulted in immediate respiratory improvement, and the patient was discharged 22 days postoperatively. Follow-up demonstrated sustained airway patency and no signs of cancer recurrence. This case highlights the feasibility and effectiveness of surgical management of PPS in centres with limited prior experience and supports mediastinal repositioning with prosthetic implants as a viable treatment option in severe cases.

BMJ Case ReportsVol. 18(8)
University Hospitals Birmingham NHS Foundation Trust (GB), Aarhus University Hospital (DK)
Good health and well-being
Openalex Percentile: Top 69%
Tracheal and airway disorders
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