Adsorption of antidepressant and cardiovascular drugs to activated charcoal: amitriptyline, bupropion, minoxidil, propranolol, and venlafaxine
This study supports the use of activated charcoal for gastrointestinal decontamination in overdoses involving amitriptyline, bupropion, minoxidil, propranolol, and venlafaxine. However, drug-specific differences in adsorption behavior suggest a need for refined dosing strategies, particularly in cases involving drugs with lower binding efficiencies.
Authors
- Stefanie A. Sydlik (ORCID: https://orcid.org/0000-0001-9375-2356)
- Hunter B. Wood (ORCID: https://orcid.org/0000-0001-5732-9649)
- Dazhe Cao (ORCID: https://orcid.org/0000-0003-2775-8527)
- Stella M. Trickett
- Joseph T. Dosch
Institutions
- Southwestern Medical Center (US)
- Carnegie Mellon University (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Clinical Toxicology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1080/15563650.2025.2532625
- Citations
- 1
- Primary Topic
- Poisoning and overdose treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.25